MAT2A-IN-9

SKU: orb1744405

Description

MAT2A-IN-9 is a potent and selective small molecule inhibitor of methionine adenosyltransferase 2A (MAT2A). This 2-oxoquinazoline derivative exhibits antitumor activity in preclinical models, showing efficacy against both lymphoma and solid tumor cell lines in vitro and in xenograft studies in vivo.

Research Area

Epigenetics & Chromatin

Key Properties

• CAS Number: 2439277-80-0
• MW: 340.69
• Purity: 99.17%
• Formula: C₁₄H₈ClF₃N₄O
• SMILES: O=C1N(C=2C(=CC=C(C(F)(F)F)N2)C(N)=N1)C3=C(Cl)C=CC=C3
• Target: Methionine Adenosyltransferase (MAT)
• Solubility: DMSO:50 mg/mL (146.76 mM)

Storage & Handling

• Storage: keep away from direct sunlight,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

MethionineAdenosyltransferase(MAT), MethionineAdenosyltransferase, Methionine Adenosyltransferase (MAT), Methionine Adenosyltransferase, GSK-4362676, IDE397, MAT

Compound Identifiers

PubChem CID

153608878