Masupirdine mesylate

SKU: orb1709193

Description

Masupirdine mesylate (SUVN-502 mesylate) is a brain-penetrant, selective 5-HT6 receptor antagonist used in research for Alzheimer's disease and dementia. It is applied in both in vitro binding studies and in vivo models to investigate cognitive and behavioral outcomes.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1791396-46-7
• MW: 670.61
• Purity: 99.57% (May vary between batches)
• Formula: C₂₃H₃₂BrN₃O₉S₃
• SMILES: CS(O)(=O)=O.CS(O)(=O)=O.COc1ccc2n(cc(CN3CCN(C)CC3)c2c1)S(=O)(=O)c1ccccc1Br
• Target: 5-HT Receptor
• Solubility: DMSO:15 mg/mL (22.37 mM)

Bioactivity

• Target IC50:
  5-HT6 Receptor:2.04 nM (Ki)

Storage & Handling

• Storage: keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

SUVN 502 Mesylate, SUVN502 Mesylate, SUVN-502 mesylate, SVN-502 mesylate, 5HTReceptor, 5HT Receptor, 5-HT6, 5-HT6 Receptor

Compound Identifiers

PubChem CID

118142730