Manzamine A hydrochloride

SKU: orb1692004

Description

Manzamine A hydrochloride is a beta-carboline alkaloid with oral activity, acting as a dual inhibitor of GSK-3β and CDK-5. It also inhibits vacuolar ATPases and autophagy, demonstrating research utility in antimalarial, anticancer, and anti-HSV-1 studies in vitro.

Research Area

Cell Biology, Infectious Disease & Virology, Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 104264-80-4
• MW: 585.23
• Formula: C₃₆H₄₅ClN₄O
• SMILES: Cl.[H][C@]12C[C@]34CN5CC[C@@]3([H])C(=C[C@@](O)(CC\C=C/CCCC5)[C@]4([H])N1CCCC\C=C/2)c1nccc2c3ccccc3[nH]c12
• Target: Others,GSK-3,CDK,Parasite,Proton pump,HSV,Autophagy

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

166638289