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Catalog Number | orb699685 |
---|---|
Category | Antibodies |
Description | Mammaglobin is a 93 amino acid glycoprotein with homology to other secretoglobin-uteroglobin family members. It was originally identified as a breast cancer restricted biomarker by differential screening. Mammaglobin related to secretoglobin family that includes human uteroglobin and lipophilin. Mammaglobin antibody stains cytoplasm of normal breast epithelial cells as well as primary and metastatic breast carcinomas. Mammaglobin expression is absent in prostate, kidney, colon, rectum, small intestine, stomach, pancreas, lung, and thyroid tissues.Mammaglobin may be used as part of an immunohistochemical panel for determination of metastatic breast carcinoma and tumor of unknown primary origin. |
Clonality | Recombinant |
Species/Host | Mouse |
Isotype | Mouse IgG2a, kappa |
Conjugation | Unconjugated |
Reactivity | Human |
UniProt ID | Q13296 |
Tested applications | IHC-P |
Dilution range | Immunohistochemistry (FFPE): 1-2ug/ml for 30 minutes at RT |
Application notes | Optimal dilution of the recombinant Mammaglobin antibody should be determined by the researcher. |
Antibody Type | Primary Antibody |
Clone Number | rMGB/4299 |
Formula | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Hazard Information | This recombinant Mammaglobin antibody is available for research use only. |
Note | For research use only |
IHC staining of FFPE human breast carcinoma with recombinant Mammaglobin antibody (clone rMGB/4299). HIER: boil tissue sections in pH9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
IHC staining of FFPE human breast carcinoma with recombinant Mammaglobin antibody (clone rMGB/4299). HIER: boil tissue sections in pH9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
SDS-PAGE analysis of purified, BSA-free recombinant Mammaglobin antibody (clone rMGB/4299) as confirmation of integrity and purity.
IHC-P, WB | |
Human | |
Mouse | |
Monoclonal | |
Unconjugated |
IF, IHC-P, WB | |
Human | |
Rabbit | |
Recombinant | |
Unconjugated |
IHC-P, WB | |
Human | |
Mouse | |
Monoclonal | |
Unconjugated |