Mal-amido-PEG7-acid

SKU: orb1940712

Description

Mal-amido-PEG7-acid is a PEG-based PROTAC linker that can be used to synthesize PROTACs.(In Vitro):PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.

Key Properties

• CAS Number: 2112731-42-5
• MW: 548.586
• Purity: >98% (HPLC)
• Formula: C₂₄H₄₀N₂O₁₂
• SMILES: OC(=O)CCOCCOCCOCCOCCOCCOCCOCCNC(=O)CCN1C(=O)C=CC1=O
• Target: HtrA2

Bioactivity

• In Vitro:
  PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Mal-NH-PEG7-COOH | Maleimide-NH-PEG7-CH2CH2COOH

Quick Database Links

Gene Symbol

HtrA2