Lincomycin

SKU: orb1708945

Description

Lincomycin is a lincosamide antibiotic derived from Streptomyces, active against susceptible Gram-positive and cell wall-less bacteria. It serves as a research tool for studying bacterial protein synthesis inhibition and antibiotic resistance mechanisms in both in vitro and in vivo models.

Research Area

Infectious Disease & Virology

Key Properties

• CAS Number: 154-21-2
• MW: 406.54
• Purity: 99.77% (May vary between batches)
• Formula: C₁₈H₃₄N₂O₆S
• SMILES: [C@@H](NC(=O)[C@@H]1C[C@@H](CCC)CN1C)([C@@H](C)O)[C@]2(O[C@H](SC)[C@H](O)[C@@H](O)[C@H]2O)[H]
• Target: Antibiotic,Antibacterial
• Solubility: DMSO:80 mg/mL (196.78 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (8.12 mM)

Bioactivity

• In Vivo:
  Lincomycin (5 g/L in drinking water for 7 days) caused intestinal and liver injury, inflammation, and gut microbiota imbalance in 21-day-old ICR mice, indicating toxicity via the gut–liver axis.

Storage & Handling

• Storage: keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Lincomycin, U 10149, U10149, U-10149

Compound Identifiers

PubChem CID

3000540