ledoxantrone

SKU: orb1980197

Description

Ledoxantrone is a synthetic benzopyranoindazole that acts as a DNA intercalator and topoisomerase II poison, stabilizing the enzyme-DNA cleavable complex and inhibiting DNA helicase. It has demonstrated antitumor activity in preclinical in vitro and in vivo studies, making it a candidate for oncology research involving DNA replication and repair mechanisms.

Research Area

Cell Biology, Molecular Biology

Key Properties

• CAS Number: 113457-05-9
• MW: 397.54
• Formula: C₂₁H₂₇N₅OS
• SMILES: OC=1C=CC2=C(SC3=C(C=CC4=C3C2=NN4CCN(CC)CC)NCCN)C1
• Target: DNA/RNA Synthesis,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

366673