LDN-91946

SKU: orb1308132

Description

LDN-91946

Research Area

Cell Biology, Molecular Biology, Protein Biochemistry

Key Properties

• CAS Number: 439946-22-2
• MW: 314.32
• Purity: 92.78% (May vary between batches)
• Formula: C₁₅H₁₀N₂O₄S
• SMILES: Nc1c(sc2[nH]c(=O)c(cc12)C(O)=O)C(=O)c1ccccc1
• Target: DUB
• Solubility: DMSO:83 mg/mL (264.06 mM)

Bioactivity

• Target IC50:
  UCHL1: 2.8 μM(ki)
• In Vitro:
  LDN-91946 demonstrates no inhibitory activity against TGase 2, Papain, and Caspase-3 at concentrations of 40 μM, and remains inactive against UCH-L3 at 20 μM. Furthermore, it exhibits no cytotoxic effects on serum-starved Neuro 2A (N2A) cells even at concentrations up to 0.1 mM.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

DUBs, Deubiquitinase, Inhibitor, LDN 91946, LDN91946, LDN-91946, inhibit, selective, UCH-L1, Ubiquitin

Compound Identifiers

PubChem CID

950368