LAU159

SKU: orb1309495

Description

LAU159 is a functionally selective positive allosteric modulator of α1β3 GABA(A) receptors, exhibiting an EC50 of 2.2 μM. This compound is a valuable research tool for investigating GABA(A) receptor subtype function in neurological research, applicable in both in vitro and ex vivo experimental models.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2055050-87-6
• MW: 325.75
• Purity: 98.65% (May vary between batches)
• Formula: C₁₇H₁₂ClN₃O₂
• SMILES: O=C1C=2C(C=3C(NC2)=CC=C(Cl)C3)=NN1C4=CC(OC)=CC=C4
• Target: GABA Receptor
• Solubility: DMSO:Slightly soluble

Bioactivity

• Target IC50:
  α1β3γ2 GABAA receptor:（EC50）2.2 μM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, Inhibitor, LAU 159, LAU159, LAU-159, GABAReceptor, GABA Receptor, Gamma-aminobutyric acid Receptor, α1β3 GABA, γ-Aminobutyric acid Receptor

Compound Identifiers

PubChem CID

124111373