Lansoprazole sulfide

SKU: orb1705226

Description

Lansoprazole sulfide (AG-177) is the active metabolite of the proton pump inhibitor lansoprazole. It exhibits antitubercular activity, inhibiting Mycobacterium tuberculosis growth in vitro with an IC50 of 0.59 µM, making it a compound of interest for infectious disease research.

Research Area

Infectious Disease & Virology, Metabolism Research

Key Properties

• CAS Number: 103577-40-8
• MW: 353.36
• Purity: 99.78% (May vary between batches)
• Formula: C₁₆H₁₄F₃N₃OS
• SMILES: FC(F)(F)COC=1C=CN=C(C1C)CSC2=NC=3C=CC=CC3N2
• Target: Drug Metabolite,Antibacterial
• Solubility: DMSO:2 mg/mL (5.66 mM)

Bioactivity

• Target IC50:
  M. tuberculosis:0.59 μM
• In Vitro:
  Lansoprazole sulfide exhibits anti-tuberculosis activity, showing an IC₅₀ of 0.59 µM against Mycobacterium tuberculosis.

Storage & Handling

• Storage: store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

AG 1777, AG1777, AG-1777, K1252, K-1252, K 1252, Lansoprazole impurity C, Lansoprazole Sulfide, Lansoprazole sulfide, H 225/18, EC 600-451-9

Compound Identifiers

PubChem CID

1094080