Labuxtinib

SKU: orb1962236

Description

Labutinib is a small molecule research compound that selectively targets and inhibits the c-kit tyrosine kinase. It is utilized in both in vitro and in vivo studies to investigate oncogenic signaling pathways, particularly in cancers like gastrointestinal stromal tumors (GIST) and mast cell disorders.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• CAS Number: 1426449-01-5
• MW: 377.37
• Purity: 99.95% (May vary between batches)
• Formula: C₂₀H₁₆FN₅O₂
• SMILES: C(NC1=CC(=CC=C1C)C=2N=C(ON2)[C@@H]3[C@@H](F)C3)(=O)C=4N5C(=NC4)C=CC=C5
• Target: c-Kit,EGFR
• Solubility: DMSO:55 mg/mL (145.75 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

cKit, c-Kit, EGFR

Compound Identifiers

PubChem CID

71280305