L-Ascorbic acid 2-phosphate

SKU: orb1706155

Description

L-ascorbic acid 2-phosphate is a stabilized vitamin C derivative used in research to promote collagen synthesis and osteogenic differentiation. It is widely applied in vitro to enhance alkaline phosphatase activity and Runx2 expression in stem cells like hASCs, supporting bone tissue engineering studies.

Research Area

Immunology & Inflammation, Metabolism Research, Signal Transduction

Key Properties

• CAS Number: 23313-12-4
• MW: 256.1
• Purity: 99.99%
• Formula: C₆H₉O₉P
• SMILES: O(P(=O)(O)O)C1=C(O)[C@@]([C@H](CO)O)(OC1=O)[H]
• Target: Endogenous Metabolite,Others,Phosphatase,Reactive Oxygen Species,ROS
• Solubility: H2O:< 1 mg/mL (insoluble);1 M HCL:20 mg/mL (78.09 mM);0.1 M HCl:10 mg/mL (39.05 mM)

Bioactivity

• In Vitro:
  L-Ascorbic acid 2-phosphate (0.1-1.5 mM, every 2-3 days for 2-3 weeks) significantly stimulated cell growth, whereas addition of L-ascorbic acid (Asc) only achieved weak growth stimulation. L-Ascorbic acid 2-phosphate (50 μM-250 μM) is required for efficient osteogenic differentiation of human adipose-derived stem cells (hASCs), and higher concentrations of AsA2-P lead to increased runx2 expression and ALP activity.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

2-Phospho-L-ascorbic acid, alkaline phosphatase, L-Ascorbic acid, LAscorbic acid 2phosphate, L-Ascorbic acid 2-phosphate, L Ascorbic acid 2 phosphate

Compound Identifiers

PubChem CID

54679073