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L-745870

SKU: orb1709297

Description

L-745870 is a brain-penetrant, orally bioavailable small molecule with high selectivity for dopamine D4 receptor antagonism. It also exhibits activity at D2, 5-HT2, and α-adrenergic receptors, making it a useful pharmacological tool for in vitro and in vivo studies of neuropsychiatric disorders such as schizophrenia.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number158985-00-3
MW326.82
FormulaC18H19ClN4
SMILESClC1=CC=C(C=C1)N2CCN(CC3=CNC=4N=CC=CC43)CC2
TargetDopamine Receptor

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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Protocol Information

L-745870 (orb1709297)

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Available Sizes

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100 mg
2 mg
$ 80.00
1 ml x 10 mM (in DMSO)
$ 110.00