KSI-6666

SKU: orb2646344

Description

KSI-6666 is a potent and orally bioavailable competitive antagonist of the S1PR1 receptor, demonstrating an IC50 of 6.4 nM. It has shown efficacy in preclinical models of autoimmune diseases, including encephalomyelitis and T-cell transfer colitis, highlighting its utility for immunology and inflammation research.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1807873-14-8
• MW: 454.91
• Formula: C₂₃H₂₆ClF₃N₂O₂
• SMILES: O=C(O)C1CN(CC2=CC(=CC=C2C)C(N(C3=CC=C(Cl)C(=C3)C(F)(F)F)CC)C)C1
• Target: LPL Receptor

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

91666634