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KM11060

SKU: orb1304503

Description

KM11060 is a small molecule corrector that addresses the F508del-CFTR trafficking defect, enhancing the delivery and functional expression of the CFTR channel at the cell surface. It is a research tool used in vitro to study cystic fibrosis pathophysiology and the rescue mechanisms of mutant CFTR.

Research Area

Cell Biology, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number774549-97-2
MW422.33
Purity98.86%
FormulaC19H17Cl2N3O2S
SMILESClc1ccc(cc1)S(=O)(=O)N1CCN(CC1)c1ccnc2cc(Cl)ccc12
TargetAutophagy,CFTR
Solubility10% DMSO+90% Corn Oil:4 mg/mL (9.47 mM);DMSO:42.2 mg/mL (99.92 mM)

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

CFTR, Cystic fibrosis transmembrane conductance regulator, Autophagy, inhibit, KM 11060, KM11060, KM-11060, Inhibitor

Similar Products

  • KM11060 [orb1224025]

    >98% (HPLC)

    774549-97-2

    422.3282

    C19H17Cl2N3O2S

    1 g, 500 mg, 200 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

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Protocol Information

KM11060 (orb1304503)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

1 ml x 10 mM (in DMSO)
$ 70.00
5 mg
$ 70.00
10 mg
$ 90.00
25 mg
$ 130.00
50 mg
$ 170.00
100 mg
$ 240.00
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