KBP-7018

SKU: orb1700250

Description

KBP-7018 is a potent and selective small molecule inhibitor targeting the fibrotic kinases c-KIT, RET, and PDGFR with IC50 values of 10 nM, 7.6 nM, and 25 nM, respectively. It is a valuable research tool for investigating fibrotic pathways and has demonstrated anti-fibrotic efficacy in preclinical in vivo models of systemic sclerosis and pulmonary fibrosis.

Research Area

Cardiovascular Research, Cell Biology, Signal Transduction

Key Properties

• CAS Number: 1613437-66-3
• MW: 538.59
• Purity: 99.73%
• Formula: C₃₁H₃₀N₄O₅
• SMILES: C(\NC=1C=C2C(=CC1)N(C(CN3CCOCC3)=O)CC2)(=C\4/C=5C(NC4=O)=CC(C(OC)=O)=CC5)/C6=CC=CC=C6
• Target: PDGFR,c-Kit,c-RET

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

136216081