JQ-1 (carboxylic acid)-NH-C2-NH-AMPRO-222

SKU: orb2945904

Description

This compound, JQ-1 (carboxylic acid)-NH-C2-NH-AMPRO-222, serves as a key intermediate for synthesizing PROTAC BRD4 Degrader-29. It contains a BRD4-targeting ligand connected to a PROTAC linker. Such intermediates are utilized in chemical biology and oncology research to develop novel protein degradation tools for in vitro studies.

Research Area

Epigenetics & Chromatin, Pharmacology & Drug Discovery

Key Properties

• MW: 827.5
• Formula: C₄₃H₅₁ClN₈O₃S₂
• SMILES: CC1=C(SC2=C1C(=N[C@H](C3=NN=C(N32)C)CC(=O)NCCNC(=O)C4=CC=C(C=C4)SCCC#CC(C5CCOCC5)N6CCC(CC6)N)C7=CC=C(C=C7)Cl)C
• Target: Target Protein Ligand-Linker Conjugates,Epigenetic Reader Domain

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172677135