JPS016 TFA

SKU: orb2279011

Description

JPS016 is a benzamide-based VHL-recruiting PROTAC that induces potent degradation of class I HDACs, specifically HDAC1 and HDAC2. This degradation leads to altered gene expression and enhanced apoptosis in cellular models like HCT116, supporting its use as a chemical probe for oncology and epigenetics research.

Research Area

Epigenetics & Chromatin, Immunology & Inflammation, Molecular Biology, Pharmacology & Drug Discovery

Key Properties

• MW: 1012.14
• Formula: C₅₀H₆₄F₃N₇O₁₀S
• Target: HDAC|||PROTACs

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

HDAC|||PROTACs