JMS-175-2

SKU: orb2695597

Description

JMS-175-2 is a potent small molecule inhibitor of the BRCC36 isopeptidase complex (BRISC) with an IC50 of 3.8 μM. It serves as a valuable research tool for investigating Type I interferon-mediated diseases, enabling both in vitro biochemical studies and in vivo models of autoimmunity and inflammation.

Research Area

Cell Biology, Epigenetics & Chromatin, Molecular Biology, Protein Biochemistry

Key Properties

• CAS Number: 3042887-70-4
• MW: 555.24
• Formula: C₂₃H₁₉Cl₄N₅O₃
• SMILES: O=C(NC1CCNCC1)C2=NN(C=C2NC(=O)C=3C(Cl)=CC=CC3Cl)C(=O)C=4C(Cl)=CC=CC4Cl
• Target: DUB

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172652623