JHU37160

• Catalog Number: orb1298442
• Category: Small Molecules
• Description: JHU37160
• CAS Number: 2369979-68-8
• Purity: 99.25%
• MW: 358.84
• SMILES: CCN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2c(F)cccc12
• Formula: C₁₉H₂₀ClFN₄
• Biological Activity: JHU37160 (JHU 37160) is a Designer Receptors Exclusively Activated by Designer Drug (DREADD) agonist with Ki of 1.9 nM and 3.6 nM for human muscarinic acetylcholine M3 receptors (hM3Dq) and hM4Di in vitro, respectively. And EC50 values are 18.5 nM and 0.2 nM for hM3Dq and hM4Di in fluorescent and BRET-based assays in HEK-293 cells, respectively.
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.