JDTic dihydrochloride

SKU: orb1709364

Description

JDTic Dihydrochloride is a potent and selective κ-opioid receptor (KOR) antagonist that inhibits dynorphin-mediated signaling. It has demonstrated antidepressant and anxiolytic properties in preclinical studies, along with efficacy in reducing relapse to substances like cocaine and nicotine in animal models, supporting its use in neuropharmacology research.

Research Area

Cardiovascular Research, Epigenetics & Chromatin, Metabolism Research, Neuroscience, Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 785835-79-2
• MW: 538.55
• Formula: C₂₈H₄₁Cl₂N₃O₃
• SMILES: Cl.Cl.CC(C)[C@@H](CN1CC[C@](C)([C@@H](C)C1)c1cccc(O)c1)NC(=O)[C@H]1Cc2ccc(O)cc2CN1
• Target: JAK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

66576991