JD-13

SKU: orb3172898

Description

JD-13 is a novel and potent Hsp90α inhibitor that binds to the ATP-binding pocket of Hsp90α (Kd = 1.60 μM), downregulates the Akt/β-catenin pathway, inhibits both wild-type and acyclovir-resistant HSV-1 infections, and alleviates skin lesions in guinea pigs caused by HSV-1 infection.

Key Properties

• CAS Number: 2969172-58-3
• MW: 436.56
• Purity: 99.69% (May vary between batches)
• Formula: C₂₅H₃₂N₄O₃
• SMILES: O=C(N)C1=CC=C(C=C1NC23CCC(O)(CC2)CC3)N4N=C(C=5C(=O)CC(C)(C)CC54)C
• Target: HSP

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

HSP