JBS Bright Red

SKU: orb65676

Description

Crystallization screening with high concentrations of precipitant and salt may lead to the formation of salt crystals. It is quite difficult to make a distinction between these false positives and true protein crystals. Staining of crystals with appropriate dyes is a very straightfor-ward method to differentiate between macromolecular crystals and salt crystals. Protein and salt crystals differ substantially in their solvent content. Small crystal dyes, like Biorbyt Bright Red, are able to permeate the solvent channels of a protein, thus coloring the protein red. In contrast, salt crystals are tightly packed and do not possess large solvent channels. They will therefore remain colourless.

Images & Validation

• Application Notes:
  Biorbyt Bright Red is a crystal dye used to stain macromolecular crystals, i.e. protein, peptide and nucleic acid crystals in order to differentiate them from small molecules and salt crystals.

Key Properties

• CAS Number: 548-24-3
• MW: Theoretical MW: 624.08 g/mol
• Formula: C₂₀H₆Br₂N₂Na₂O₉
• SMILES: c1(c(cc2c(c1Br)Oc1c(C32c2ccccc2C(=O)O3)cc(c(c1Br)[O-])[N+](=O)[O-])[N+](=O)[O-])[O-].[Na+].[Na+]

Storage & Handling

• Storage: store at ambient temperature
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Eosin Scarlet

Compound Identifiers

PubChem CID

12961637