Jatrophane 5

SKU: orb1683799

Description

Jatrophane 5 is a potent P-glycoprotein (P-gp) inhibitor, exhibiting superior activity to R(+)-verapamil and tariquidar in multidrug-resistant DLD1-TxR colorectal cancer cells. This small molecule is a valuable research tool for investigating MDR mechanisms and overcoming chemoresistance in both in vitro and in vivo oncology models.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 210108-89-7
• MW: 779.836
• Formula: C₄₁H₄₉NO₁₄
• SMILES: [H][C@]12[C@@H](OC(=O)c3ccccc3)[C@@](C)(C[C@]1(O)[C@@H](OC(C)=O)[C@@H](C)\C=C\C(C)(C)[C@H](OC(=O)c1cccnc1)[C@H](O)[C@@H](OC(C)=O)C(=C)[C@@H]2OC(C)=O)OC(C)=O |t:26|
• Target: P-gp

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

15828276