JAMM protein inhibitor 2

SKU: orb1297822

Description

JAMM protein inhibitor 2 (Acetamide, 2-(2-ethylphenoxy)-N-[2-methyl-4-(1-pyrrolidinyl)phenyl]-) is a small molecule JAMM protease inhibitor with reported IC50 values of 10 µM, 46 µM, and 89 µM against thrombin, Rpn11, and MMP2, respectively. It serves as a research tool for anticancer studies, applicable in both in vitro enzymatic assays and cellular mechanism of action investigations.

Research Area

Cell Biology, Molecular Biology, Pharmacology & Drug Discovery, Protein Biochemistry

Key Properties

• CAS Number: 848249-35-4
• MW: 338.44
• Purity: 98.82% (May vary between batches)
• Formula: C₂₁H₂₆N₂O₂
• SMILES: CCc1ccccc1OCC(=O)Nc1ccc(cc1C)N1CCCC1
• Target: Others
• Solubility: DMSO:4 mg/mL (11.82 mM)

Bioactivity

• Target IC50:
  RPN11:46 μM|Thrombin:10 μM|MMP2:89 μM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Acetamide, 2-(2-ethylphenoxy)-N-[2-methyl-4-(1-pyrrolidinyl)phenyl]-, Anticancer, Inhibitor, inhibit, JAMM protease, JAMM protein inhibitor 2, JAMM protein inhibitor 2 , JAMM protein inhibitor2, JAMM protein inhibitor-2

Compound Identifiers

PubChem CID

4853066