Jagged-1 (188-204)

SKU: orb1679617

Description

Jagged-1 (188-204) is a peptide fragment of the JAG-1 protein, a key Notch ligand that drives epidermal differentiation. In research, it is used in vitro to model keratinocyte stratification and NF-κB activation under high-calcium conditions, supporting studies in skin biology and epithelial development.

Research Area

Neuroscience, Protein Biochemistry, Stem Cell & Developmental Biology

Key Properties

• Target: Gamma-secretase
• CAS Number: 219127-21-6
• MW: 2107.4
• Formula: C₉₃H₁₂₇N₂₅O₂₆S₃
• SMILES: O=C(N[C@@H](Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc2ccccc2)C(=O)NCC(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N4CCC[C@H]4C(=O)N[C@@H](CCCNC(=N)N)C(=O)O)[C@H](Cc5ccc(O)cc5)NC(=O)[C@H](Cc6ccc(O)cc6)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@@H](N)CS

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

16136414