Ixazomib (Standard)

SKU: orb3141149

Description

Ixazomib (Standard) is a reference standard for research and analysis in studies involving Ixazomib. Ixazomib (MLN2238) , a second generation, boron-containing peptide proteasome inhibitor (PI), inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome (IC50/Ki: 3.4/0.93 nM, in cell-free assays), also inhibits the caspase-like (β1) and trypsin-like (β2) proteolytic sites (IC50: 31/3500 nM).

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1072833-77-2
• MW: 361.03
• Formula: C₁₄H₁₉BCl₂N₂O₄
• SMILES: CC(C)C[C@H](NC(=O)CNC(=O)c1cc(Cl)ccc1Cl)B(O)O
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Others