ITF5924

SKU: orb2565936

Description

ITF5924 is a highly selective and potent HDAC6 inhibitor (IC50 = 7.7 nM) featuring a difluoromethyl-1,3,4-oxadiazole moiety. It acts as a slow-binding substrate analog, forming a stable, long-lasting complex with the enzyme after catalytic ring opening. This inhibitor is a valuable chemical tool for probing HDAC6 function in oncology and neurology research models.

Research Area

Epigenetics & Chromatin, Molecular Biology

Key Properties

• CAS Number: 2760854-72-4
• MW: 436.42
• Formula: C₂₁H₁₈F₂N₈O
• SMILES: C(N1C=C(N=N1)C2=CC=C(NC=3NCCN3)C=C2)C4=CC=C(C=C4)C=5OC(C(F)F)=NN5
• Target: HDAC

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

162722395