Isobutylshikonin

SKU: orb1297533

Description

Isobutylshikonin is a potent antioxidant compound, demonstrating strong ABTS+ radical scavenging activity and moderate DPPH• inhibition. It is widely used in biochemical research to study oxidative stress mechanisms in both cellular (in vitro) and animal (in vivo) models.

Key Properties

• CAS Number: 52438-12-7
• MW: 358.39
• Purity: 99.91% (May vary between batches)
• Formula: C₂₀H₂₂O₆
• SMILES: CC(C)C(=O)O[C@H](CC=C(C)C)C1=CC(=O)c2c(O)ccc(O)c2C1=O
• Target: Others
• Solubility: DMSO:Slightly soluble

Bioactivity

• In Vitro:
  Five red shikonin pigments, deoxyshikonin, shikonin, acetylshikonin, Isobutylshikonin, and beta-hydroxyisovalerylshikonin, were isolated from the roots of Lithospermum erythrorhizon cultivated in Korea. The purified pigments were red, purple, and blue at acidic, neutral, and alkaline pH values, respectively. Physical stability of the purified pigments against heat and light in an aqueous solution was examined for possible value-added food colorants. The thermal degradation reactions were carried out at pH 3.0 (50 mM glycine buffer) in 50% EtOH/H(2)O. Deoxyshikonin (t(1/2) = 14.6 h, 60 degrees C) and isobutylshikinin (t(1/2) = 19.3 h, 60 degrees C) are relatively less stable than other shikonin derivatives (t(1/2) = 40-50 h, 60 degrees C). Activation energies of thermal degradation of the isolated pigments were calculated. The activation energy of deoxyshikonin was the highest (12.5 kcal mol(-)(1)) and that of beta-hydroxyisovalerylshikonin was the lowest (1.71 kcal mol(-)(1)) value

Storage & Handling

• Storage: keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

DPPH, Inhibitor, Isobutylshikonin, inhibit

Compound Identifiers

PubChem CID

479500