Irloxacin

SKU: orb1297952

Description

Irloxacin is a novel quinolone derivative exhibiting enhanced antibacterial activity under acidic conditions. Its broad in vitro spectrum against gram-positive and gram-negative bacteria supports research in antimicrobial development and infectious disease studies.

Research Area

Infectious Disease & Virology

Key Properties

• CAS Number: 91524-15-1
• MW: 300.28
• Purity: 99.71% (May vary between batches)
• Formula: C₁₆H₁₃FN₂O₃
• SMILES: CCn1cc(C(O)=O)c(=O)c2cc(F)c(cc12)-n1cccc1
• Target: Antibacterial
• Solubility: DMSO:25 mg/mL (83.26 mM)

Bioactivity

• In Vitro:
  We have compared the in vitro activity of irloxacin against mycobacteria (20 M. tuberculosis, 17 M. avium, 5 Mycobacterium bovis, 5 Mycobacterium chelonae, 5 Mycobacterium fortuitum and 1 Mycobacterium gadium) using the Bactec at pH 6.8 and 5.0, with other quinolones (ofloxacin, ciprofloxacin, pefloxacin and 27753 RP). All quinolones tested showed good activity against mycobacteria at pH 6.8 and 5.0. Irloxacin at pH 5.0 had a greater activity against M. avium.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

acid pH, antibacterial agent, Bacterial, gram-negative bacteria, gram-positive, Irloxacin, inhibit, Inhibitor, oral, Pirfloxacin

Compound Identifiers

PubChem CID

65828