Irinotecan-d10 Hydrochloride

SKU: orb2300226

Description

Irinotecan-d10 Hydrochloride (CAS 100286-90-6 for the non-deuterated form) is a deuterated analog of the topoisomerase I inhibitor Irinotecan HCl. This prodrug is metabolized to the active SN-38, which induces DNA damage and apoptosis, making it a key tool for oncology research in both in vitro and in vivo models of colorectal and other cancers.

Research Area

Cell Biology, Molecular Biology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 718612-62-5
• MW: 633.20
• Formula: C₃₃H₂₉D₁₀ClN₄O₆
• SMILES: C(C)C1=C2C(C=3N(C2)C(=O)C4=C(C3)[C@](CC)(O)C(=O)OC4)=NC=5C1=CC(OC(=O)N6CCC(CC6)N7C(C(C(C(C7([2H])[2H])([2H])[2H])([2H])[2H])([2H])[2H])([2H])[2H])=CC5.Cl
• Target: Autophagy,Topoisomerase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

46781987