Iopromide

SKU: orb1224112

Description

Iopromide is a molecule used as a contrast medium. It is marketed under the name Ultravist which is produced by Bayer Healthcare. It is a low osmolar, non-ionic contrast agent for intravascular use.(In Vivo):Contrast medium-induced nephropathy can be induced by tail intravenous administration of iopromide. In randomized controlled trials, the global image quality and diagnostic quality with iobitridol does not differ from those with other low-osmolar contrast media (iohexol, iopromide, iopamidol, iomeprol and ioxaglate) or the iso-osmolar contrast medium iodixanol in adults or children undergoing radiographic imaging. Large post-marketing surveillance studies have confirmed that iobitridol produces good or excellent opacification and is an effective contrast agent in the vast majority of patients. Iobitridol is generally well tolerated and had a tolerability profile similar to that of other low-osmolar and iso-osmolar contrast media. Thus, iobitridol is an effective intravascular agent for contrast enhancement in diagnostic imaging.

Key Properties

• CAS Number: 73334-07-3
• MW: 791.12
• Purity: >98% (HPLC)
• Formula: C₁₈H₂₄I₃N₃O₈
• SMILES: c1(c(c(c(I)c(c1I)NC(COC)=O)C(NC[C@@H](CO)O)=O)I)C(N(C[C@@H](CO)O)C)=O
• Target: Others
• Solubility: Soluble in DMSO

Bioactivity

• In Vivo:
  Contrast medium-induced nephropathy can be induced by tail intravenous administration of iopromide. In randomized controlled trials, the global image quality and diagnostic quality with iobitridol does not differ from those with other low-osmolar contrast media (iohexol, iopromide, iopamidol, iomeprol and ioxaglate) or the iso-osmolar contrast medium iodixanol in adults or children undergoing radiographic imaging. Large post-marketing surveillance studies have confirmed that iobitridol produces good or excellent opacification and is an effective contrast agent in the vast majority of patients. Iobitridol is generally well tolerated and had a tolerability profile similar to that of other low-osmolar and iso-osmolar contrast media. Thus, iobitridol is an effective intravascular agent for contrast enhancement in diagnostic imaging.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Ultravist

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