Imazamox

SKU: orb1219085

Description

Imazamox is a systemic herbicide with high selectivity, high activity, safety and broadspectrum activity. Imazamox inhibits the production of acetolactate synthase (ALS) in plants, which would then inhibit plant growth and ultimately lead to plant death.

Key Properties

• CAS Number: 114311-32-9
• MW: 305.33
• Purity: >98% (HPLC)
• Formula: C₁₅H₁₉N₃O₄
• SMILES: CC(C)C1(C)N=C(c2ncc(COC)cc2C(O)=O)NC1=O
• Target: others
• Solubility: DMSO:18 mg/mL (58.95 mM; Need ultrasonic)

Bioactivity

• In Vivo:
  Imazamox (12-36 mg/kg; intraperitoneal injection; for 24-72 hours; male Sprague-Dawley rats) treatment induces toxic effects in the liver and pancreas of Sprague Dawley rats. Necrotic and degenerative changes are detected in hepatocytes at the two highest doses. Imazamox treatment reduces the size of the β-islet cells, and also induces an elevation in serum glucose and calcium. Animal model: 50 male Sprague-Dawley rats (300 ± 10 g). Dosage: 12 mg/kg, 24 mg/kg and 36 mg/kg. Administration: Intraperitoneal injection; for 24 hours, 48 hours or 72 hours. Result: Induced toxic effects in the liver and pancreas.
• In Vitro:
  Half-life of Imazamox in the soil ranges from 1 to 3 months exhibit low mammalian toxicity. Plants are treated with Imazamox (250 μM) in the nutrient solution and harvested 7 days after. Imazamox is mainly accumulated in V. sativa, six fold higher than those detected in P. vulgaris.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CL29926 | (±)-Imazamox

Quick Database Links

Gene Symbol

others