IM-54

SKU: orb1703364

Description

IM-54 is a potent and selective small-molecule inhibitor of necrotic cell death, demonstrating cell permeability. It is utilized in both in vitro and in vivo research to investigate necrosis in fields such as ischemia-reperfusion injury and neurodegenerative disease models.

Research Area

Cell Biology, Signal Transduction

Key Properties

• CAS Number: 861891-50-1
• MW: 325.4
• Purity: 99.24% (May vary between batches)
• Formula: C₁₉H₂₃N₃O₂
• SMILES: CCCCCNC1=C(C(=O)N(C)C1=O)c1cn(C)c2ccccc12
• Target: MLK,Necroptosis
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.15 mM);DMSO:55 mg/mL (169.02 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

IM54, IM-54, IM 54, necrosis(MLKL)

Compound Identifiers

PubChem CID

16760577