ILS-920

SKU: orb1707926

Description

ILS-920 is a neuroprotective rapamycin analog with reduced immunosuppressive activity. It selectively binds FKBP52 (200-fold over FKBP12) and the β1-subunit of L-type VGCCs, making it a research tool for studying neuroprotection and calcium signaling in models of neurological disease.

Research Area

Cell Biology, Immunology & Inflammation, Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 892494-07-4
• MW: 1023.3
• Formula: C₅₇H₈₆N₂O₁₄
• SMILES: C[C@@H]1[C@]2(N(O[C@](CC2)(/C=C(\C)/[C@@H](OC)C[C@]3(O[C@@](O)(C(=O)C(=O)N4[C@](C(=O)O[C@]([C@@H](C[C@H]5C[C@@H](OC)[C@H](O)CC5)C)(CC(=O)[C@H](C)/C=C(\C)/[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C1)[H])(CCCC4)[H])[C@H](C)CC3)[H])[H])C6=CC=CC=C6)[H]
• Target: Others,FKBP,Calcium Channel

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

58974612