Human TRIM21 Protein (Biotin)

SKU: orb611144

Description

TRIM21 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The 52 kDa Ro protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus

Images & Validation

• Application Notes:
  Binds IgG type human auto antibodies. Functional Streptavidin based ELISA test (analysis of positive/negative samples.)

Key Properties

• Source: Sf9 insect cells
• Species/Host: Insect
• Immunogen: TRIM21 is expressed with a -6x His tag at N-terminus
• Molecular Weight: TRIM21 Human Recombinant, Biotin produced in SF9 is a glycosylated, polypeptide chain having a calculated molecular mass of 52kDa
• Purity: Greater than 80% as determined by SDS-PAGE

Storage & Handling

• Storage: Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles
• Form/Appearance: Sterile Filtered clear solution
• Buffer/Preservatives: TRIM21 solution is supplied in 20mM HEPES pH-7.6, 0.01mM EDTA and 0.02% SDS
• Disclaimer: For research use only

Alternative Names

52 kDa Ro protein, Sjoegren syndrome type A antigen, SS-A, Ro(SS-A), 52 kDa ribonucleoprotein autoantigen Ro/SS-A, Tripartite motif-containing protein 21, RING finger protein 81, TRIM21, RNF81, RO52, SSA1, SSA, RO-52