Human TNFα

• Catalog Number: orb1729592
• Category: Proteins
• Description: Tumor necrosis factor alpha (TNF-α),is a member of the TNF superfamily. It is a pleiotropic molecule that plays a central role in inflammation and immune system development. TNF-α is produced by a wide variety of cell types including lymphoid cells. TNFa matures through separation of the extracellular domain from rest of the molecule. It forms a soluble trimer which binds the trimeric TNF receptor (TNFR). TNF-α is a key cytokine in the development of several inflammatory disorders
• Species/Host: E. coli
• Conjugation: Unconjugated
• Tag: Histidine
• Reactivity: Human, Mouse
• Form/Appearance: Lyophilized
• Concentration: 1mg/mL
• Buffer/Preservatives: No preservative
• Purity: ≥98%
• Protein Sequence: MSTESMIRDVELAEEALPKKTGGPQGSRRCLFLSLFSFLIVAGATTLFCLLHFGVIGPQREESPRDLSLISPLAQAVRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELRDNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL
• MW: ~26 kDa
• Tested applications: SDS-PAGE
• Dilution range: NA
• Application notes: For research use only
• Expression System: Intercellular
• Endotoxins: Not tested
• Source: Human
• Biological Origin: Recombinant protein expressed as His tage protein in E.coli
• Solubility (25°C): Soluble in PBS at 25°C
• Storage: After reconstitution, store at -20°C; Avoid repeated freeze thaw
• Alternative names: TNFSF1A, TNFSF2
• Hazard Information: For Research use only
• Note: For research use only