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Human TNFα

Human TNFα

Catalog Number: orb1729592

DispatchUsually dispatched within 5-10 working days
$ 550.00
Catalog Numberorb1729592
CategoryProteins
DescriptionTumor necrosis factor alpha (TNF-α),is a member of the TNF superfamily. It is a pleiotropic molecule that plays a central role in inflammation and immune system development. TNF-α is produced by a wide variety of cell types including lymphoid cells. TNFa matures through separation of the extracellular domain from rest of the molecule. It forms a soluble trimer which binds the trimeric TNF receptor (TNFR). TNF-α is a key cytokine in the development of several inflammatory disorders
Species/HostE. coli
Tested applicationsSDS-PAGE
ReactivityHuman, Mouse
TagHistidine
Concentration1mg/mL
Dilution rangeNA
Form/AppearanceLyophilized
Purity≥98%
ConjugationUnconjugated
MW~26 kDa
Hazard InformationFor Research use only
Solubility (25°C)Soluble in PBS at 25°C
Protein SequenceMSTESMIRDVELAEEALPKKTGGPQGSRRCLFLSLFSFLIVAGATTLFCLLHFGVIGPQREESPRDLSLISPLAQAVRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELRDNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL
SourceHuman
Expression SystemIntercellular
Biological OriginRecombinant protein expressed as His tage protein in E.coli
EndotoxinsNot tested
StorageAfter reconstitution, store at -20°C; Avoid repeated freeze thaw
Buffer/PreservativesNo preservative
Alternative namesTNFSF1A, TNFSF2
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NoteFor research use only
Application notesFor research use only
Expiration Date6 months from date of receipt.
  • Human TNF-alpha Protein [orb257883]

    Unconjugated

    95%

    17.4 kDa

    Human TNF-alpha, premium grade (orb257883) is expressed from human 293 cells (HEK293). It contains AA Val 77 - Leu 233 (Accession # P01375-1).

    1 mg, 100 μg, 20 μg
  • Human TNF-alpha Protein, His Tag [orb383503]

    Unconjugated

    95%

    18.3 kDa

    Human TNF-alpha, His Tag (active trimer) (MALS verified) (orb383503) is expressed from human 293 cells (HEK293). It contains AA Val 77 - Leu 233 (Accession # NP_000585.2).

    1 mg, 100 μg
  • Human TNFa Protein, His Tag [orb689423]

    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

    The protein has a predicted molecular mass of 18.1 kDa after removal of the signal peptide.

    Mammalian

    10 μg, 50 μg, 100 μg
  • Canine TNF-alpha Protein, His Tag [orb762406]

    Unconjugated

    90%

    18.6 kDa

    Canine TNF-alpha, His Tag (orb762406) is expressed from human 293 cells (HEK293). It contains AA Val 77 - Leu 233 (Accession # P51742-1).

    100 μg, 1 mg
  • Mouse TNF-alpha Protein, His Tag [orb1496307]

    Unconjugated

    95%

    19.1 kDa

    Mouse TNF-alpha, His Tag (orb1496307) is expressed from human 293 cells (HEK293). It contains AA Leu 80 - Leu 235 (Accession # P06804).

    100 μg, 1 mg