Human Tau-441 K18 (P301L) Pre-formed Fibrils Protein, Tag Free

SKU: orb3158021

Description

This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq, Jul 2008]

Research Area

Neuroscience

Images & Validation

• Application Notes:
  This protein carries no "tag". The protein has a calculated MW of 13.7 kDa.

Key Properties

• Expression System: E. coli
• Target: Tau
• Reactivity: Human
• Tag: Native
• Molecular Weight: 13.7 kDa
• Expression Region: Gln 244 - Glu 372
• Purity: 95%
• Endotoxins: 1.0 EU per μg
• Conjugation: Unconjugated

Storage & Handling

• Storage: -70°C
• Form/Appearance: Liquid
• Buffer/Preservatives: PBS, pH 7.4
• Expiration Date: 6 months from date of receipt.
• Dry Ice Shipping: Please note: This product requires shipment on dry ice. A dry ice surcharge will apply.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Tau

UniProt

P10636

RefSeq:P301, P10636