Human DLL3 Protein, Llama IgG2b Fc Tag, low endotoxin

SKU: orb3002139

Description

Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands.May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm. DLL3 protein is expressed on the surface of tumor cells but not in normal adult tissues.

Images & Validation

• Application Notes:
  This protein carries a llama IgG2b Fc tag at the N-terminus. The protein has a calculated MW of 76.8 kDa. The protein migrates as 55-65 kDa and 70-90 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Key Properties

• Expression System: HEK293
• Target: DLL3
• Reactivity: Human
• Tag: N-LlamaFc(LlamaIgG2b)
• Molecular Weight: 76.8 kDa
• Expression Region: Ala 27 - Leu 492
• Purity: 90%
• Endotoxins: 0.01 EU per μg
• Conjugation: Unconjugated

Storage & Handling

• Storage: -20°C
• Form/Appearance: Powder
• Buffer/Preservatives: 50 mM Tris, 100 mM Glycine, 225 mM Arginine, 150 mM NaCl, pH 7.5
• Expiration Date: 6 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

DLL3

RefSeq:Q9NYJ7