Human DLL3 (353-492) Protein

SKU: orb1152435

Description

Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands.May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm. DLL3 protein is expressed on the surface of tumor cells but not in normal adult tissues.

Images & Validation

• Application Notes:
  This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 16.4 kDa. The protein migrates as 18 kDa and 19-21 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Key Properties

• Source: Human DLL3 (353-492) , His Tag (orb1152435) is expressed from human 293 cells (HEK293). It contains AA Arg 353 - Leu 492 (Accession # Q9NYJ7-1).
• Expression System: HEK293
• Target: DLL3
• Reactivity: Human
• Tag: C-10×His
• Molecular Weight: 16.4 kDa
• Expression Region: Arg 353 - Leu 492
• Purity: 90%
• Endotoxins: 1.0 EU per μg
• Conjugation: Unconjugated

Storage & Handling

• Storage: -70℃
• Form/Appearance: Liquid
• Buffer/Preservatives: PBS, pH7.4
• Expiration Date: 6 months from date of receipt.
• Dry Ice Shipping: Please note: This product requires shipment on dry ice. A dry ice surcharge will apply.
• Disclaimer: For research use only

Alternative Names

Delta3,delta-like 3 (Drosophila),delta-like protein 3,DLL3,Pudgy,SCDO1,SCDO1delta3

Quick Database Links

Gene Symbol

DLL3

UniProt

Q9NYJ7

RefSeq:Q9NYJ7