Human BACE-1 Protein, Fc Tag

SKU: orb257212

Description

Human BACE-1, Fc Tag is expressed from human 293 cells (HEK293). It contains AA Thr 22 - Thr 457 (Accession # NP_036236.1).

Images & Validation

• Application Notes:
  This protein carries a human IgG1 Fc tag at the C-terminus. The Human BACE-1 will be further processed into mature form (Glu 46-Thr 457). The protein has a calculated MW of 75.2 kDa (pro-form) and 72.6 kDa (mature-form). The protein migrates as 30-32 kDa, 55-65 kDa and 90-100 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Key Properties

• Expression System: HEK293
• Target: BACE-1
• Reactivity: Human
• Tag: C-Fc
• Molecular Weight: 75.2 kDa & 72.6 kDa
• Expression Region: Thr 22 - Thr 457
• Purity: 90%
• Endotoxins: 1.0 EU per μg
• Conjugation: Unconjugated

Storage & Handling

• Storage: -20°C to -70°C for 12 months in lyophilized state;. -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower
• Form/Appearance: Powder
• Buffer/Preservatives: 50 mM Tris, 100 mM Glycine, pH 7.5
• Disclaimer: For research use only

SDS-PAGE analysis of Human BACE-1 protein

Quick Database Links

Gene Symbol

BACE-1

UniProt

NP_036236.1