HSD17B13-IN-61

SKU: orb2566033

Description

HSD17B13-IN-61 (Compound 132) is a potent small-molecule inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 ≤ 0.1 μM against estradiol. It is a valuable research tool for investigating the role of HSD17B13 in liver diseases such as NAFLD/NASH, metabolic disorders, and drug-induced liver injury (DILI) in both in vitro and in vivo models.

Research Area

Metabolism Research

Key Properties

• CAS Number: 2770247-26-0
• MW: 542.27
• Formula: C₂₃H₁₃Cl₂F₄N₃O₄
• SMILES: N(C(=O)C1=CC(Cl)=C(O)C(Cl)=C1)C2=C3C(N=CN(CC4=C(OC(F)(F)F)C=CC=C4)C3=O)=C(F)C=C2
• Target: Dehydrogenase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

163301109