HS56

SKU: orb1741139

Description

HS56 is a potent ATP-competitive inhibitor targeting DAPK3 and Pim kinases, with sub-micromolar K i values for DAPK3 and Pim-3. It serves as a key research tool for studying hypertension, demonstrated by its ability to inhibit myosin light chain phosphorylation in vitro and reduce blood pressure in hypertensive mouse models.

Research Area

Cell Biology, Epigenetics & Chromatin, Signal Transduction

Key Properties

• CAS Number: 922050-57-5
• MW: 317.75
• Formula: C₁₃H₈ClN₅OS
• SMILES: O=C1C2=C(N(N=C2)C3=CC(Cl)=CC=C3)NC(SCC#N)=N1
• Target: DAPK,Others,Pim

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

136637454