Homocarbonyltopsentin

SKU: orb1707935

Description

Homocarbonyltopsentin is a small molecule that binds the TSL2 RNA pentaloop, shifting its conformation to a triloop. This structural change enhances SMN2 exon 7 splicing with an EC50 of 16 μM, making it a valuable research tool for studying spinal muscular atrophy (SMA) therapeutics in vitro.

Research Area

Cell Biology, Molecular Biology

Key Properties

• CAS Number: 172286-77-0
• MW: 370.36
• Formula: C₂₁H₁₄N₄O₃
• SMILES: Oc1ccc2c(c[nH]c2c1)C(=O)c1ncc([nH]1)C(=O)c1c[nH]c2ccccc12
• Target: Others,DNA/RNA Synthesis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

11326167