Holanamine

SKU: orb2815329

Description

Holanamine is a non-competitive inhibitor of Leishmania donovani topoisomerase IB (LdTop1B), exerting its antileishmanial activity via hydrogen bonding and hydrophobic interactions with the enzyme's large subunit. This small molecule is a useful research tool for studying leishmaniasis pathogenesis and validating LdTop1B as a drug target in both in vitro and in vivo experimental models.

Key Properties

• CAS Number: 6869-29-0
• MW: 325.45
• Formula: C₂₁H₂₇NO₂
• SMILES: C[C@H]1[C@@]2([C@@]3([C@]([C@]4([C@]([C@H](O)C3)([C@]5(C)C(CC4)=CC(=O)C=C5)[H])[H])(CC2)[H])C=N1)[H]

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

76308534