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Catalog Number | orb1740115 |
---|---|
Category | Small Molecules |
Description | HMS607P03 |
CAS Number | 361198-09-6 |
Purity | 0.98 |
MW | 535.04 |
SMILES | O=C1N(C2=NC=3C(S2)=CC=CC3)N=C(CSC4=CC=C(Cl)C=C4)C1=CNCC=5C=C6C(=CC5)OCO6 |
Formula | C26H19ClN4O3S2 |
Biological Activity | HMS607P03 is an activator of SIRT1 which induces autophagic cell death via the AMPK-mTOR-ULK complex and induces mitophagy by the SIRT1-PINK1-Parkin pathway. HMS607P03 downregulates 14-3-3γ, catalase, profilin-1, and HSP90α. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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