Cart summary

You have no items in your shopping cart.

HIV Type-1 p24 Antibody

HIV Type-1 p24 Antibody

Catalog Number: orb2638066

DispatchUsually dispatched within 5-10 working days
$ 780.00
Catalog Numberorb2638066
CategoryAntibodies
DescriptionHuman immunodeficiency virus (HIV) is a retrovirus that causes acquired immune deficiency syndrome (AIDS), a condition in humans in which the immune system begins to fail, leading to life-threatening opportunistic infections. HIV mainly infects vital cells in the human immune system such as helper T cells (specifically CD4+ T cells), macrophages and dendritic cells. Two species of HIV infect humans: HIV-1 and HIV-2, with HIV-1 being the more virulent strain. The gag gene of human immunodeficiency virus 1 (HIV-1) encodes a precursor protein known as Pr55Gag. The viral protease PR cleaves this precursor to generate p17, p24, p7, and p6 proteins, which are required for virus particle assembly. HIV-1 Gag p24 is a capsid protein that constitutes the core of AIDS virus HIV-1. p6 and p7 are the components of the nucleocapsid, and p17 provides a protective matrix. HIV-1 Gag p24 is indispensable to the reproduction of AIDS virus and constitutes an essential element for the AIDS virus particle construction. As this protein is detectable from the early stage of AIDS virus infection, its measurement is commonly used as an indicator of HIV-1 infection and viral load.
ClonalityMonoclonal
Species/HostMouse
IsotypeMouse IgG1, kappa
ConjugationUnconjugated
ReactivityHuman
Buffer/Preservatives0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin (US sourced) and 0.05% sodium azide
PurityProtein G affinity chromatography
ImmunogenRecombinant HIV-1 Gag p24 protein was used as the immunogen for this antibody.
Tested applicationsELISA, ICC, IF
Dilution rangeELISA (order BSA/sodium azide-free format for coating),Immunocytochemistry (Acetone- or paraformaldehyde-fixed): 0.5-1ug/ml for 30 min,Immunofluorescence: 0.5-1ug/ml
Application notesThe concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the HIV Type-1 p24 antibody to be titered up or down for optimal performance.
Antibody TypePrimary Antibody
Clone NumberHIV1-24/661
Formula0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Hazard InformationThis HIV type-1 p24 antibody is available for research use only.
NoteFor research use only
Entrez155348