HIV-1 Integrase p31

SKU: orb85294

Description

TheE.coli derived recombinant protein is a non-glycosylated polypeptide chain, containing the HIV-1 immunodominant regions from the p31 protein (intergrase) 9-289 amino acids, fused with a GST tag at N-terminus. HIV belongs to the retrovirus family, distinguished by possession of a viral reverse transcriptase that transcribes viral RNA into DNA which is integrated into the host-cell genome. The human immunodeficiency virus (HIV) integrase (IN), one of the three virally encoded enzymes required for HIV-1 replication, must covalently join the viral cDNA into a host chromosome for productive HIV infection.

Images & Validation

• Application Notes:
  May be used in ELISA and Western blots, excellent antigen for early detection of HIV seroconvertors with minimal specificity problems.

Key Properties

• Molecular Weight: Theoretical MW: 32 kDa
• Purity: > 95% (SDS-PAGE, HPLC)

Storage & Handling

• Storage: store at -20 °C
• Form/Appearance: liquid (Supplied in 25 mM Tris-HCl pH 8.0, 1.5 M urea, 0.2% Triton-X and 50% glycerol)
• Disclaimer: For research use only