hDHODH-IN-4

SKU: orb1709877

Description

hDHODH-IN-4 (DHODH-IN-5) is a potent human dihydroorotate dehydrogenase (DHODH) inhibitor, exhibiting a pIC50 of 7.8 on the recombinant enzyme and a pMIC50 of 8.8 against measles virus replication. This small molecule is a valuable tool for studying DHODH's role in viral infections and immunology in both cellular and animal models.

Research Area

Cell Biology, Infectious Disease & Virology, Metabolism Research, Molecular Biology

Key Properties

• CAS Number: 1644156-56-8
• MW: 364.44
• Purity: 99.31% (May vary between batches)
• Formula: C₂₁H₂₄N₄O₂
• SMILES: CC(C)Oc1nn(c(C)c1C(O)c1ccccc1)-c1ncc(cn1)C1CC1
• Target: DNA/RNA Synthesis,Influenza Virus,Dehydrogenase
• Solubility: 10% DMSO+90% Corn Oil:5 mg/mL (13.72 mM);DMSO:112.5 mg/mL (308.69 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

hDHODH, hDHODH-IN-4, DHODH-IN-5

Compound Identifiers

PubChem CID

118430507