hDHODH-IN-1

SKU: orb1309582

Description

hDHODH-IN-1

Research Area

Cell Biology, Metabolism Research, Molecular Biology

Key Properties

• CAS Number: 1173715-42-8
• MW: 278.31
• Purity: 99.75% (May vary between batches)
• Formula: C₁₇H₁₄N₂O₂
• SMILES: C\C(O)=C(/C#N)C(=O)Nc1ccc(cc1)-c1ccccc1
• Target: Dehydrogenase,DNA/RNA Synthesis
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.19 mM);DMSO:50 mg/mL (179.66 mM)

Bioactivity

• In Vitro:
  Human dihydroorotate dehydrogenase (hDHODH), a class-2 dihydroorotate dehydrogenase, is essential for proliferating-cell viability. Consequently, inhibitors targeting hDHODH activity have been developed to address conditions such as cancers, inflammatory diseases, autoimmune disorders, and multiple sclerosis.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

dehydrogenase, DHODH, dihydroorotate, DNA/RNA Synthesis, anti-inflammatory, human, hDHODH, hDHODH IN 1, hDHODHIN1, hDHODH-IN-1, LDH, Lactate Dehydrogenase, Inhibitor, inhibit, proliferating-cell

Compound Identifiers

PubChem CID

54727972